在生长抑素受体SPECT/CT检查中，99mTc-HYNIC-TOC摄取增加可模拟胰腺钩突部的恶性病变。
99mTc-HYNIC-TOC increased uptake can mimic malignancy in the pancreas uncinate process at somatostatin receptor SPECT/CT.
作者信息
Yamaga Lilian Yuri Itaya, Neto Guilherme Campos Carvalho, da Cunha Marcelo Livorsi, Osawa Akemi, Oliveira Julio Cesar Silveira, Fonseca Ricardo Quartim, Nogueira Solange Amorim, Wagner Jairo, Funari Marcelo Gusmão
机构信息
Imaging Department, Albert Einstein Hospital, Av. Albert Einstein, 627, São Paulo, CEP: 05651-090, Brazil.
出版信息
Radiol Med. 2016 Mar;121(3):225-8. doi: 10.1007/s11547-015-0593-2. Epub 2015 Nov 12.
OBJECTIVE
The aim of this study was to assess the occurrence and frequency of increased physiologic uptake of 99mTc-HYNIC-TOC by the uncinate process of the pancreas in SPECT/CT images.
METHODS
Forty-six scans of 41 patients were evaluated retrospectively. The uptake of 99mTc-HYNIC-TOC was considered to be physiologic in patients with normal findings at dedicated abdominal CT or MR and lack of neoplastic lesions in clinical follow-ups. The intensity of uncinate process uptake was compared to the uptake of the normal liver.
RESULTS
Focal uptake was attributed to the presence of pancreatic NET in 5 patients. Among the 36 patients without any evidence of malignancy in CT, MR and follow-up, 7 (19.4 %) showed increased uptake in the uncinate process. The intensity of uptake was lesser in 3 (8.3 %), similar in 3 and greater than the normal liver in 1 (2.8 %) case.
CONCLUSION
Increased 99mTc-HYNIC-TOC uptake occurred in 19.4 % of those subjects without any evidence of neuroendocrine tumor in the uncinate process.
目的
本研究旨在评估在SPECT/CT图像中胰腺钩突对99mTc-HYNIC-TOC生理性摄取增加的发生率和频率。
方法
对41例患者的46次扫描进行回顾性评估。在专门的腹部CT或MR检查结果正常且临床随访中无肿瘤病变的患者中，99mTc-HYNIC-TOC的摄取被认为是生理性的。将钩突摄取的强度与正常肝脏的摄取进行比较。
结果
5例患者的局灶性摄取归因于胰腺神经内分泌肿瘤。在36例CT、MR和随访中无任何恶性证据的患者中，7例（19.4%）钩突摄取增加。摄取强度在3例（8.3%）中较低，3例相似，1例（2.8%）大于正常肝脏。
结论
在钩突无任何神经内分泌肿瘤证据的受试者中，19.4%出现99mTc-HYNIC-TOC摄取增加。
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