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中国急性心肌梗死基于指南管理的临床特征及改善:一项全国性回顾性分析

Clinical characteristics and improvement of the guideline-based management of acute myocardial infarction in China: a national retrospective analysis.

作者信息

Wang Lechen, Zhou You, Qian Cheng, Wang Yanggan

机构信息

Department of Cardiology, Zhongnan Hospital of Wuhan University & the Medical Research Institute of Wuhan University, Wuhan University, Wuhan, China.

出版信息

Oncotarget. 2017 Jul 11;8(28):46540-46548. doi: 10.18632/oncotarget.14890.

Abstract

OBJECTIVE

This study is to document the clinical characteristics and improvement in management of acute myocardial infarction (AMI) in Chinese population.

RESULTS

This study included 64,654 patients (23,805 patients in 2011, 40,849 patients in 2013), of which STEMI and NSTEMI account for 85.09% and 14.91%, respectively. From 2011 to 2013, significant improvement has been achieved in the recanalization rate of PCI (96.01% vs. 98.63%, P < 0.001) and in-hospital deaths (4.52% vs. 3.55%, P = 0.038). Although the time of door-to-balloon and the duration of PCI were satisfactorily controlled within 90min and 60min, respectively, the onset-to-FMC time (≈3.5h) and door-to-thrombolysis time (≈1.1h) limited the efficiency of management. The total cost of medical care showed no increase from 2011 to 2013, but the patient's paid Portion decreased from 20.33% to 13.96%.

MATERIALS AND METHODS

The AMI patients admitted in the general hospitals in 2011 and 2013 were retrospectively analyzed according to the data reported to the Single Disease Quality Control Information Systemissued by Chinese Hospital Association.

CONCLUSION

Compared to the Western countries, STEMI accounted for a larger portion of AMI, and the AMI management in China basically meets the standards of the quality control of guidelines. With improvement of management, there was no increase in the total medical cost, while the patient's paid portion was actually reduced. In future, improvement of transportation strategy and the public medical education are recommended to shorten the onset-to-FMC time to further improve the outcome of AMI patients.

摘要

目的

本研究旨在记录中国人群急性心肌梗死(AMI)的临床特征及管理改善情况。

结果

本研究纳入64,654例患者(2011年23,805例,2013年40,849例),其中ST段抬高型心肌梗死(STEMI)和非ST段抬高型心肌梗死(NSTEMI)分别占85.09%和14.91%。从2011年到2013年,经皮冠状动脉介入治疗(PCI)的再灌注率(96.01%对98.63%,P<0.001)和院内死亡率(4.52%对3.55%,P = 0.038)有显著改善。尽管门球时间和PCI持续时间分别令人满意地控制在90分钟和60分钟内,但发病至首次医疗接触时间(约3.5小时)和门至溶栓时间(约1.1小时)限制了管理效率。2011年至2013年医疗总费用未增加,但患者自付比例从20.33%降至13.96%。

材料与方法

根据上报至中国医院协会发布的单病种质量控制信息系统的数据,对2011年和2013年综合医院收治的AMI患者进行回顾性分析。

结论

与西方国家相比,STEMI在AMI中所占比例更大,中国的AMI管理基本符合指南质量控制标准。随着管理的改善,医疗总费用未增加,而患者自付比例实际上有所降低。未来,建议改进转运策略和公众医学教育以缩短发病至首次医疗接触时间,进一步改善AMI患者的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/936b/5542290/3fa778b748ba/oncotarget-08-46540-g001.jpg

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