Chamberlain Winston, Austin Ariana, Terry Mark, Jeng Bennie H, Rose-Nussbaumer Jennifer
Department of Ophthalmology, Oregon Health Sciences University, Portland, USA.
Francis I. Proctor Foundation, University of California, San Francisco, San Francisco, USA.
J Clin Exp Ophthalmol. 2016 Oct;7(5). doi: 10.4172/2155-9570.1000608. Epub 2016 Oct 27.
To survey cornea specialists' opinions on different endothelial keratoplasty techniques and to gauge the perceived need for and utility of a randomized controlled trial (RCT) comparing them.
A short survey was distributed to a group of cornea specialists at the Endothelial Keratoplasty Group meeting at the American Academy of Ophthalmology meeting in November 2015.
Thirty-three of 80 practicing surgeons present at the EKG meeting participated in the survey, yielding a response rate of 41%. Ninety-seven percent (n=32) of our respondents reported performing Descemet's Stripping Endothelial Keratoplasty (DSEK) regularly, and 70% reported having performed Descemet's Membrane Endothelial Keratoplasty (DMEK) at least once (n=23). While most respondents (n=26, 79%) thought there was at least some evidence that DMEK is superior to DSEK in terms of visual acuity, there was less certainty about comparing ultrathin-DSEK (UT-DSEK) to DMEK with 48% (n=16) thinking there was at least some evidence of DMEK's superiority, 6% (n=2) thinking there was at least some evidence of UT-DSEK's superiority, and 30% (n=10) unsure. Seventy-two percent (n=23) of respondents thought an RCT comparing visual acuity outcomes in UT-DSEK versus DMEK would be at least moderately beneficial, and 82% (n=27) reported they were at least moderately likely to change their EK technique based on the results of said RCT.
There is substantial interest in an RCT comparing visual acuity outcomes in UT-DSEK versus DMEK.
调查角膜专家对不同内皮角膜移植技术的看法,并评估比较这些技术的随机对照试验(RCT)的必要性和实用性。
在2015年11月美国眼科学会会议的内皮角膜移植组会议上,向一组角膜专家发放了一份简短的调查问卷。
出席内皮角膜移植会议的80名执业外科医生中有33人参与了调查,回复率为41%。97%(n = 32)的受访者报告定期进行后弹力层剥除内皮角膜移植术(DSEK),70%报告至少进行过一次后弹力层内皮角膜移植术(DMEK)(n = 23)。虽然大多数受访者(n = 26,79%)认为至少有一些证据表明DMEK在视力方面优于DSEK,但在比较超薄DSEK(UT-DSEK)和DMEK时,确定性较低,48%(n = 16)的人认为至少有一些证据表明DMEK更具优势,6%(n = 2)的人认为至少有一些证据表明UT-DSEK更具优势,30%(n = 10)不确定。72%(n = 23)的受访者认为比较UT-DSEK和DMEK视力结果的RCT至少会有一定益处,82%(n = 27)报告他们至少有一定可能性根据该RCT的结果改变其内皮角膜移植技术。
人们对比较UT-DSEK和DMEK视力结果的RCT有很大兴趣。