Okubo Ayaka, Takahashi Kazuhiro, Akasaka Toshihide, Amano Hiroo
Department of Dermatology, School of Medicine, Iwate Medical University, Morioka, Japan.
Department of Dermatology, Kitakami Saiseikai Hospital, Kitakami, Japan.
J Dermatol. 2017 Jun;44(6):713-716. doi: 10.1111/1346-8138.13756. Epub 2017 Feb 2.
Morbihan disease (MD) is rosacea-like disease characterized by persistent lymphedema on the upper half of the face. Currently, there is no established standard treatment for MD. Recently, MD has been reported to be associated with the infiltration of mast cells. The aim of this study was to investigate the association of treatment response and mast cell infiltration in MD. We report four cases of MD that were successfully treated with long-term oral doxycycline therapy.
莫尔比昂病(MD)是一种类似酒渣鼻的疾病,其特征为面部上半部分持续性淋巴水肿。目前,尚无针对MD的既定标准治疗方法。最近,有报道称MD与肥大细胞浸润有关。本研究的目的是调查MD的治疗反应与肥大细胞浸润之间的关联。我们报告了4例通过长期口服多西环素治疗成功治愈的MD病例。