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Reduction in pulmonary and hepatic respiratory cytochrome contents by fly ash inhalation in rats.

作者信息

Chauhan S S, Tyagi S R, Kapoor R K, Misra U K

机构信息

Department of Biochemistry, V.P. Chest Institute, University of Delhi, India.

出版信息

Toxicol Lett. 1989 Oct;49(1):15-20. doi: 10.1016/0378-4274(89)90095-7.

DOI:10.1016/0378-4274(89)90095-7
PMID:2815111
Abstract

Exposure of rats to fly ash for 15 days, 6 hours daily, inhibited pulmonary and hepatic NADH-oxidase activity. The content of cytochrome b and cytochromes a + a3 was significantly lower in the lungs of the fly-ash-exposed group. However, in liver, fly ash exposure reduced the cytochrome a + a3 level without affecting the cytochrome b content, indicating a tissue-specific effect. Mitochondrial protein content in both organs was the same in both groups.

摘要

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