Chiosea Simion I
Department of Pathology, Presbyterian University Hospital, University of Pittsburgh Medical Center, A610.3, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
Surg Pathol Clin. 2017 Mar;10(1):1-14. doi: 10.1016/j.path.2016.10.002. Epub 2016 Dec 10.
The surgical method of margin sampling affects local control, pathologists' approach to margin sampling, and clarity of pathology reports. Studies have shown that exclusive reliance on tumor bed margins is associated with worse local control and should be avoided. En bloc resections and margins obtained from the resection specimen remain the "gold standard." Successful surgical treatment of early carcinomas of the oral cavity relies on close cooperation between surgeons and pathologists on issues of specimen orientation and margin sampling.
切缘取样的手术方法会影响局部控制、病理学家对切缘取样的方法以及病理报告的清晰度。研究表明，单纯依赖肿瘤床切缘与较差的局部控制相关，应予以避免。整块切除以及从切除标本获取的切缘仍是“金标准”。口腔早期癌的成功手术治疗依赖于外科医生和病理学家在标本定向和切缘取样问题上的密切合作。
