Karran Emma L, Traeger Adrian C, McAuley James H, Hillier Susan L, Yau Yun-Hom, Moseley G Lorimer
Sansom Institute for Health Research, University of South Australia, Adelaide, Australia; Royal Adelaide Hospital, Adelaide, Australia.
Neuroscience Research Australia, Sydney, Australia; Prince of Wales Clinical School, University of New South Wales, Sydney, Australia.
J Pain. 2017 Jun;18(6):673-686. doi: 10.1016/j.jpain.2016.12.020. Epub 2017 Jan 30.
Prognostic screening in patients with low back pain (LBP) offers a practical approach to guiding clinical decisions. Whether screening is helpful in secondary care is unclear. This prospective cohort study in adults with LBP placed on outpatient clinic waiting lists, compared the performance of the short-form Orebro Musculoskeletal Pain Screening Questionnaire, the Predicting the Inception of Chronic Pain Tool, and the STarT Back Tool. We assessed predictive validity for outcome at 4-month follow-up, by calculating estimates of discrimination, calibration, and overall performance. We applied a decision curve analysis approach to describe the clinical value of screening in this setting via comparison with a 'treat-all' strategy. Complete data were available for 89% of enrolled participants (n = 195). Eighty-four percent reported 'poor outcome' at follow-up. The area under the receiver operating characteristic curve (95% confidence interval) was .66 (.54-.78) for the Orebro Musculoskeletal Pain Screening Questionnaire, .61 (.49-.73) for the Predicting the Inception of Chronic Pain Tool, and .69 (.51-.80) for the STarT Back Tool. All instruments were miscalibrated and underestimated risk. The decision curve analysis indicated that, in this setting, prognostic screening does not add value over and above a treat-all approach. The potential for LBP patients to be misclassified using screening and the high incidence of nonrecovery indicate that care decisions should be made with the assumption that all patients are 'at risk.'
This article presents a head-to-head comparison of 3 LBP screening instruments in a secondary care setting. Early patient screening is likely to hold little clinical value in this setting and care pathways that consider all patients at risk of a poor outcome are suggested to be most appropriate.
对腰痛(LBP)患者进行预后筛查为指导临床决策提供了一种实用方法。筛查在二级医疗保健中是否有用尚不清楚。这项针对列入门诊候诊名单的成年LBP患者的前瞻性队列研究,比较了简版奥勒布鲁肌肉骨骼疼痛筛查问卷、慢性疼痛起始预测工具和STarT Back工具的性能。我们通过计算区分度、校准度和整体性能的估计值,评估了4个月随访时结果的预测效度。我们应用决策曲线分析方法,通过与“全部治疗”策略比较,描述了在这种情况下筛查的临床价值。89%的登记参与者(n = 195)可获得完整数据。84%的参与者在随访时报告“预后不良”。奥勒布鲁肌肉骨骼疼痛筛查问卷的受试者工作特征曲线下面积(95%置信区间)为0.66(0.54 - 0.78),慢性疼痛起始预测工具为0.61(0.49 - 0.73),STarT Back工具为0.69(0.51 - 0.80)。所有工具均校准错误且低估了风险。决策曲线分析表明,在这种情况下,预后筛查在“全部治疗”方法之外并无额外价值。使用筛查对LBP患者进行错误分类的可能性以及高复发率表明,应在假定所有患者“有风险”的前提下做出护理决策。
本文在二级医疗保健环境中对3种LBP筛查工具进行了直接比较。在这种情况下,早期患者筛查可能几乎没有临床价值,建议采用考虑所有预后不良风险患者的护理路径最为合适。