Sano Itsuki, Katanuma Akio, Yane Kei, Kin Toshifumi, Nagai Kazumasa, Yamazaki Hajime, Koga Hideaki, Kitagawa Koh, Yokoyama Kensuke, Ikarashi Satoshi, Takahashi Kuniyuki, Maguchi Hiroyuki, Omori Yuko, Shinohara Toshiya
Center for Gastroenterology, Teine-Keijinkai Hospital, Japan.
Intern Med. 2017;56(3):301-305. doi: 10.2169/internalmedicine.56.7213. Epub 2017 Feb 1.
Pancreatic metastasis from colorectal cancer is rare, and there have been only a few reports of its preoperative diagnosis by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) with immunohistochemical staining. We herein describe the case of a 77-year-old woman in whom a solitary mass in the pancreatic tail was detected 11 years after rectal cancer resection. The patient also had a history of pulmonary tumor resection. We performed EUS-FNA and a histopathological examination showed adenocarcinoma with CD20+, CD7-, and CDX2+ (similar to her rectal cancer). EUS-FNA enabled a histopathological examination, including immunohistochemical staining, which helped to confirm the diagnosis of pancreatic and pulmonary metastasis from rectal cancer.
结直肠癌的胰腺转移罕见，仅有少数关于通过内镜超声引导下细针穿刺活检（EUS-FNA）及免疫组织化学染色进行术前诊断的报道。我们在此描述一名77岁女性的病例，该患者在直肠癌切除术后11年被检测出胰尾部有一个孤立性肿块。患者既往有肺部肿瘤切除史。我们进行了EUS-FNA，组织病理学检查显示为腺癌，CD20+、CD7-、CDX2+（与她的直肠癌相似）。EUS-FNA使得包括免疫组织化学染色在内的组织病理学检查得以进行，这有助于确诊直肠癌的胰腺和肺转移。
