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一例与永存原始玻璃体增生症及彼得斯异常相关的牵牛花综合征病例。

A case of morning glory syndrome associated with persistent hyperplastic primary vitreous and Peters' anomaly.

作者信息

Muslubas Isil Sayman, Hocaoglu Mumin, Arf Serra, Karacorlu Murat

机构信息

Istanbul Retina Institute, Istanbul, Turkey.

出版信息

GMS Ophthalmol Cases. 2017 Jan 17;7:Doc02. doi: 10.3205/oc000053. eCollection 2017.

DOI:10.3205/oc000053
PMID:28154792
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5244077/
Abstract

We report a case of morning glory syndrome (MGS) associated with persistent hyperplastic primary vitreous (PHPV) and Peters' anomaly. A 2-day-old girl, born at term with a birth weight of 3,350 g was diagnosed with Peters' anomaly, cataract, microphthalmia, PHPV, and MGS. A right limbal lensectomy and vitrectomy with stalk cauterization was performed 8 days later. No early postoperative complication occurred, the family was discharged with advice on medication, and follow-up examination was scheduled. The case report reveals the coexistence of PHPV, Peters' anomaly, and MGS, which may suggest a genetic link.

摘要

我们报告一例牵牛花综合征（MGS）合并永存原始玻璃体增生症（PHPV）和彼得斯异常的病例。一名足月出生、体重3350克的2日龄女婴被诊断为彼得斯异常、白内障、小眼症、PHPV和MGS。8天后进行了右角膜缘晶状体切除术和玻璃体切除术并烧灼了视茎。术后早期未出现并发症，家属带药出院，并安排了随访检查。该病例报告显示了PHPV、彼得斯异常和MGS的共存，这可能提示存在遗传联系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca70/5244077/1ac6014f9e7a/OC-07-02-g-004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca70/5244077/bc0f99df441b/OC-07-02-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca70/5244077/914ea1dbe679/OC-07-02-g-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca70/5244077/9ff593548579/OC-07-02-g-003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca70/5244077/1ac6014f9e7a/OC-07-02-g-004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca70/5244077/bc0f99df441b/OC-07-02-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca70/5244077/914ea1dbe679/OC-07-02-g-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca70/5244077/9ff593548579/OC-07-02-g-003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca70/5244077/1ac6014f9e7a/OC-07-02-g-004.jpg

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本文引用的文献

1
Clinical characteristics and treatment of 22 eyes of morning glory syndrome associated with persistent hyperplastic primary vitreous.临床特点和治疗 22 例永存原始玻璃体增生症合并牵牛花综合征眼。
Br J Ophthalmol. 2013 Oct;97(10):1262-7. doi: 10.1136/bjophthalmol-2013-303565. Epub 2013 Jul 22.
2
Color Doppler imaging of eyes with persistent fetal vasculature.永存胎儿血管性眼部的彩色多普勒成像。
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GMS Ophthalmol Cases. 2020 Oct 9;10:Doc42. doi: 10.3205/oc000169. eCollection 2020.
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Update on the morning glory disc anomaly.牵牛花盘状异常的最新情况。
Ophthalmic Genet. 2008 Jun;29(2):47-52. doi: 10.1080/13816810801901876.
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Mutations of the PAX6 gene detected in patients with a variety of optic-nerve malformations.在患有各种视神经畸形的患者中检测到PAX6基因的突变。
Am J Hum Genet. 2003 Jun;72(6):1565-70. doi: 10.1086/375555. Epub 2003 Apr 29.
7
Histopathological examination of two cases of anterior staphyloma associated with Peters' anomaly and persistent hyperplastic primary vitreous.两例与彼得斯异常和永存原始玻璃体增生症相关的前葡萄肿的组织病理学检查。
Br J Ophthalmol. 2001 Dec;85(12):1421-5. doi: 10.1136/bjo.85.12.1421.
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Persistent hyperplastic primary vitreous.永存原始玻璃体增生症
Clin Eye Vis Care. 2000 Dec;12(3-4):131-137. doi: 10.1016/s0953-4431(00)00054-0.
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Morning glory syndrome associated with marked persistent hyperplastic primary vitreous and lens colobomas.牵牛花综合征伴显著持续性增生性原始玻璃体和晶状体缺损。
Br J Ophthalmol. 1989 Aug;73(8):684-6. doi: 10.1136/bjo.73.8.684.
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Morning glory syndrome: a histopathological study.牵牛花综合征：一项组织病理学研究。
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