Singh Neha, Agrawal Siddharth, Mishra Pallavi
Department of Ophthalmology, King George Medical University, Lucknow, Uttar Pradesh, India.
GMS Ophthalmol Cases. 2020 Oct 9;10:Doc42. doi: 10.3205/oc000169. eCollection 2020.
Primary hyperplastic persistent vitreous (PHPV) or persistent fetal vasculature is a rare clinical entity that presents with leucocoria, microphthalmos, and cataract. It is mostly unilateral. Here we present a report of two cases of bilateral PHPV. One of the patients had associated Peters' anomaly. The entity closely mimics retinoblastoma and should be kept as a differential diagnosis of bilateral leucocoria. Examination under anesthesia, ultrasound B-scan, and aqueous lactate dehydrogenase levels helped us reach the diagnosis and differentiate it from the more serious entity retinoblastoma.
原发性增生性永存玻璃体（PHPV）或永存胎儿血管系统是一种罕见的临床病症，表现为白瞳症、小眼球和白内障。多数为单侧发病。在此，我们报告两例双侧PHPV病例。其中一名患者合并彼得斯异常。该病症极易与视网膜母细胞瘤混淆，在诊断双侧白瞳症时应将其列为鉴别诊断对象。麻醉下检查、B超扫描及房水乳酸脱氢酶水平检测有助于我们做出诊断，并将其与更严重的视网膜母细胞瘤区分开来。
