Gu Zhaoyong, Pan Youlian, Qiao Aike, Hu Xingjian, Dong Nianguo, Li Xiaofeng, Liu Yinglong, Shang Deguang
College of Life Science and Bio-Engineering, Beijing University of Technology, Pinleyuan, Chaoyang District, Beijing, China.
College of Mechanical Engineering and Applied Electronics Technology, Beijing University of Technology, Pinleyuan, Chaoyang District, Beijing, China.
Biomed Eng Online. 2016 Dec 28;15(Suppl 2):150. doi: 10.1186/s12938-016-0264-0.
Modeling neo-aortic valve for arterial switch surgical planning to simulate the neo-aortic valve closure performance.
We created five geometrical models of neo-aortic valve, namely model A, model B, model C, model D and model E with different size of sinotubular junction or sinus. The nodes at the ends of aorta and left ventricle duct fixed all the degrees of freedom. Transvalvular pressure of normal diastolic blood pressure of 54 mmHg was applied on the neo-aortic valve cusps. The neo-aortic valve closure performance was investigated by the parameters, such as stress of neo-aortic root, variation of neo-aortic valve ring as well as aortic valve cusps contact force in the cardiac diastole.
The maximum stress of the five neo-aortic valves were 96.29, 98.34, 96.28, 98.26, and 90.60 kPa, respectively. Compared among five neo-aortic valve, aortic valve cusps contact forces were changed by 43.33, -10.00% enlarging or narrowing the sinotubular junction by 20% respectively based on the reference model A. The cusps contact forces were changed by 6.67, -23.33% with sinus diameter varying 1.2 times and 0.8 times respectively.
Comparing with stress of healthy adult subjects, the neo-aortic valve of infant creates lower stress. It is evident that enlarging or narrowing the sinotubular junction within a range of 20% can increase or decrease the maximum stress and aortic valve cusps contact force of neo-aortic valve.
为动脉调转手术规划构建新主动脉瓣模型，以模拟新主动脉瓣关闭性能。
我们创建了五个新主动脉瓣几何模型，即模型A、模型B、模型C、模型D和模型E，其窦管交界或窦的尺寸不同。主动脉和左心室导管末端的节点固定了所有自由度。将54 mmHg的正常舒张压经瓣膜压力施加于新主动脉瓣叶上。通过新主动脉根部应力、新主动脉瓣环变化以及心脏舒张期主动脉瓣叶接触力等参数研究新主动脉瓣关闭性能。
五个新主动脉瓣的最大应力分别为96.29、98.34、96.28、98.26和90.60 kPa。在五个新主动脉瓣之间进行比较，基于参考模型A，将窦管交界分别扩大或缩小20%时，主动脉瓣叶接触力分别变化43.33%、-10.00%。当窦直径分别变化1.2倍和0.8倍时，瓣叶接触力分别变化6.67%、-23.33%。
与健康成人受试者的应力相比，婴儿的新主动脉瓣产生的应力较低。显然，在20%的范围内扩大或缩小窦管交界可增加或降低新主动脉瓣的最大应力和主动脉瓣叶接触力。
