Thorpy Michael, Morse Anne Marie
Sleep-Wake Disorders Center, Montefiore Medical Center, and Albert Einstein College of Medicine, Bronx, NY, USA.
Sleep-Wake Disorders Center, Montefiore Medical Center, and Albert Einstein College of Medicine, Bronx, NY, USA.
Sleep Med Clin. 2017 Mar;12(1):61-71. doi: 10.1016/j.jsmc.2016.10.001.
The burden of narcolepsy is likely the result of 2 main aspects: the clinical difficulties and disability incurred as a direct effect of the disorder and the socioeconomic burden. The clinical burden includes the symptoms, diagnosis, comorbidities, treatment, and even mortality that can be associated with narcolepsy. Lifelong therapy is necessary for these patients. Effective treatment results in long-term benefits from both patient and societal perspectives by improving clinical outcomes, potentially enabling improved education and increased employment and work productivity, and quality of life. Thus, reducing the time to appropriate management results in improved outcomes in these patients.
该疾病直接导致的临床困难和残疾以及社会经济负担。临床负担包括与发作性睡病相关的症状、诊断、合并症、治疗，甚至死亡率。这些患者需要终身治疗。有效的治疗从患者和社会角度都能带来长期益处，通过改善临床结果，有可能促进教育改善、增加就业和提高工作效率以及生活质量。因此，缩短获得适当治疗的时间可改善这些患者的预后。
