Waterer Grant W
Univeristy of Western Australia, Level 4 MRF Building, Royal Perth Hospital, Wellington Street, Perth 6000, Australia; Northwestern University, 420 East Superior Street, Chicago, IL 60611, USA.
Clin Chest Med. 2017 Mar;38(1):21-28. doi: 10.1016/j.ccm.2016.11.004. Epub 2016 Dec 21.
The 'atypical' pathogens causing pneumonia have long been problematic for physicians because we have had to rely on serologic tests to make a diagnosis. The introduction of polymerase chain reaction techniques revolutionized the diagnosis of respiratory infections and now a new wave of technologies promising faster, cheaper, and more comprehensive testing are becoming available. This review focuses principally on the diagnosis of Legionella, Mycoplasma, and influenza infections, but also covers recent publications on the cutting edge of diagnostic tools likely to transform the field of infectious diseases over the coming decade.
长期以来，引起肺炎的“非典型”病原体一直给医生带来困扰，因为我们不得不依靠血清学检测来进行诊断。聚合酶链反应技术的引入彻底改变了呼吸道感染的诊断方式，如今，一波有望实现更快、更便宜且更全面检测的新技术正逐渐问世。本综述主要聚焦于军团菌、支原体和流感感染的诊断，但也涵盖了近期有关诊断工具前沿领域的出版物，这些工具可能在未来十年改变传染病领域。
