Cacho Nicole Theresa, Parker Leslie A, Neu Josef
Division of Neonatology, Department of Pediatrics, University of Florida, 1600 Southwest Archer Road, HD-118, Gainesville, FL 32610, USA.
Biobehavioral Nursing Science, College of Nursing, University of Florida, PO Box 100187, HPNP 2227, Gainesville, FL 32610-0187, USA.
Clin Perinatol. 2017 Mar;44(1):49-67. doi: 10.1016/j.clp.2016.11.009. Epub 2016 Dec 24.
This article summarizes evidence regarding whether a donor human milk (DHM) and/or an exclusively human milk (EHM) diet decreases the incidence of necrotizing enterocolitis (NEC) and the dose of human milk (HM) necessary to reduce the risk of NEC in premature infants. Additional research regarding protection afforded by DHM and EHM is necessary as well as research elucidating the exact dose of HM necessary for NEC risk reduction. Research is also needed to determine whether there is a dose-dependent effect of DHM, a combination of mother's own milk and DHM, and an EHM diet on NEC incidence.
本文总结了关于捐赠人乳(DHM)和/或纯人乳(EHM)饮食是否能降低坏死性小肠结肠炎(NEC)发病率以及降低早产儿患NEC风险所需的人乳(HM)剂量的证据。关于DHM和EHM提供的保护作用还需要进行更多研究,同时也需要研究阐明降低NEC风险所需的确切HM剂量。还需要开展研究,以确定DHM、母亲自身乳汁与DHM的组合以及EHM饮食对NEC发病率是否存在剂量依赖性效应。