Polster J, Wuisman P, Härle A, Matthiass H H, Brinckmann P
Orthop. Univ.-Klinik, Münster/Westf.
Z Orthop Ihre Grenzgeb. 1989 Jul-Aug;127(4):414-7. doi: 10.1055/s-2008-1044690.
The authors report on the clinical course of 31 patients with primary tumors or metastases of the spine which were treated with the vertebral body implant and Palacos, i.e., composite osteosynthesis. The goal of therapy is to relieve the spinal cord and the nerve roots and to restore the supporting function of the spine. Subjective and objective improvement was found in 64% of the patients; the result was unchanged in 23%, and further symptoms developed in 13%. The tumor-specific breakdown revealed that overall survival was somewhat more than two years in plasmocytoma cases and ten months in metastasis cases. In almost all cases in which an improvement in initial symptoms was achieved postoperatively, this improvement was permanent. With the surgical technique applied here spinal stability can be restored and the patients can also be mobilized quickly.
作者报告了31例原发性脊柱肿瘤或脊柱转移瘤患者采用椎体植入物和帕拉科斯（Palacos）进行治疗的临床过程，即复合骨合成术。治疗的目标是缓解脊髓和神经根受压，并恢复脊柱的支撑功能。64%的患者有主观和客观改善；23%的患者结果无变化，13%的患者出现了进一步的症状。肿瘤特异性分析显示，浆细胞瘤患者的总生存期略超过两年，转移瘤患者为十个月。在几乎所有术后初始症状得到改善的病例中，这种改善都是永久性的。采用此处应用的手术技术，可以恢复脊柱稳定性，患者也能够迅速恢复活动能力。
