Fujimoto N, Adachi-Usami E
Nippon Ganka Gakkai Zasshi. 1989 Jun;93(6):646-50.
We compared the visual field within 10 degrees with the latency and amplitude of the P100 component of pattern visually evoked cortical potentials (PVECPs) in optic neuritis. Twenty five eyes of 17 cases with optic neuritis suffered from multiple sclerosis (MS) and in 21 eyes of 17 cases optic neuritis was caused by unknown etiology. The visual field was tested by program 31 of the automated perimeter Octopus. PVECPs were recorded with a television system. The visual field was considered to be abnormal for when at least one abnormal point was found within a 10-degree field. P100 peak latency of PVECPs with above normal mean latency plus 2SD was defined as abnormally prolonged. The abnormalities found by 10-degree visual field and PVECPs latency correlated significantly both in cases of MS and unknown cause. The eyes with mean loss of over 4dB within a 10-degree visual field invariably had a delayed latency. Those with an abnormal central point or abnormal points in the lower part within 10-degree visual field had a delayed latency. The latency was estimated in relation to causes, age, visual acuity and visual field. The cases with worse vision or worse field showed a tendency to have a prolonged latency. In unilateral cases the ratio of PVECPs amplitude between affected eyes and healthy fellow eyes was studied. The eyes which had abnormal visual field within 10 degrees and a delayed latency showed reduced amplitude of at most 61% compared with that of the healthy fellow eyes(ABSTRACT TRUNCATED AT 250 WORDS)
我们比较了视神经炎患者10度视野范围内的情况与图形视觉诱发电位（PVECPs）P100成分的潜伏期和波幅。17例视神经炎患者中，25只眼患有多发性硬化（MS），17例中的21只眼视神经炎病因不明。使用自动视野计Octopus的程序31测试视野。通过电视系统记录PVECPs。当在10度视野内至少发现一个异常点时，视野被认为异常。PVECPs的P100峰潜伏期超过正常平均潜伏期加2个标准差被定义为异常延长。在MS和病因不明的病例中，10度视野检查发现的异常与PVECPs潜伏期显著相关。在10度视野内平均损失超过4dB的眼睛潜伏期总是延迟。在10度视野内中心点异常或下部有异常点的眼睛潜伏期延迟。根据病因、年龄、视力和视野评估潜伏期。视力或视野较差的病例潜伏期有延长的趋势。在单侧病例中，研究了患眼与健侧眼之间PVECPs波幅的比率。10度视野内视野异常且潜伏期延迟的眼睛与健侧眼相比，波幅最多降低61%（摘要截短于250字）
