Shimada Y, Adachi-Usami E, Murayama K
Department of Ophthalmology, Chiba University, Chuo-ku, Japan.
Acta Ophthalmol Scand. 1997 Jun;75(3):277-80. doi: 10.1111/j.1600-0420.1997.tb00773.x.
To investigate the macular contribution to the amplitude and latency of pattern visual evoked cortical potentials (PVECPs), we recorded PVECPs in patients with unilateral macular disease (retinal diseases involving the macular region) and optic neuritis. We selected patients with visual acuities better than 0.3, which is thought to be the minimum acuity to provide clearly discernible responses. The visual stimulus was a checkerboard. We varied the check size in 4 steps as 7, 14, 28, and 56 min of arc, and the contrast was 20% or 80%. The amplitude of the sinusoidal wave of steady-state VECPs (12 Hz) and the P100 component of a transient VECP (3 Hz) were measured. Significant attenuation and delay of PVECPs in the affected eye were found in the macular disease group. Macular disease may cause an increase of VECP latency. However, VECP seemed to be a more sensitive test of optic nerve disease than of macular disease, when patients had similar visual acuities.
为了研究黄斑对图形视觉诱发电位（PVECP）的波幅和潜伏期的影响，我们记录了单侧黄斑疾病（累及黄斑区的视网膜疾病）患者和视神经炎患者的PVECP。我们选择视力优于0.3的患者，0.3被认为是能够提供清晰可辨反应的最低视力。视觉刺激为棋盘格。我们将方格大小分4档变化，分别为7、14、28和56分视角，对比度为20%或80%。测量了稳态VECP（12Hz）正弦波的波幅和瞬态VECP（3Hz）的P100成分。黄斑疾病组患眼的PVECP出现了明显的波幅衰减和潜伏期延迟。黄斑疾病可能会导致VECP潜伏期延长。然而，当患者视力相似时，VECP对视神经疾病似乎比对黄斑疾病更敏感。
