Minamikawa M, Yamamoto K, Okuma H, Uyama M
Nippon Ganka Gakkai Zasshi. 1989 Jun;93(6):691-7.
Experimental retinal branch vein occlusion was produced in monkeys (macaca irus) by dye laser photocoagulation (yellow wavelength 577nm The 920 ARGON/DYE Laser System, Coherent Radiation). The Clinical process was observed based on ophthalmoscopic and fluorescein angiographic alterations which occur during the natural history of experimental branch vein occlusion. Immediately after occlusion, venous dilatation, retinal edema and punctate hemorrhage, were recognized by ophthalmoscopy, and leakage of dye from postcapillary venules, followed later by additional leakage from large veins were observed frequently by fluorescein angiography. Circulatory disturbances remained over 3-4 days, and the retinal branch vein occlusion were persisted. Ten days later, a non-perfusion area was observed by fluorescein angiography. More than 1 year later, these nonperfusion area remained.
通过染料激光光凝术（黄色波长577nm，920氩离子/染料激光系统，相干辐射公司）在恒河猴（猕猴）身上制造实验性视网膜分支静脉阻塞。基于在实验性分支静脉阻塞自然病程中出现的检眼镜和荧光素血管造影改变来观察临床过程。阻塞后立即通过检眼镜检查发现静脉扩张、视网膜水肿和点状出血，通过荧光素血管造影经常观察到染料从毛细血管后小静脉渗漏，随后大静脉出现额外渗漏。循环障碍持续3 - 4天，视网膜分支静脉阻塞持续存在。10天后，通过荧光素血管造影观察到一个无灌注区。1年多后，这些无灌注区仍然存在。
