Department of Reconstructive Plastic Surgery, Karolinska University Hospital, 171 76 Stockholm, Sweden; Department of Molecular Medicine and Surgery, Karolinska Institutet, 171 77 Stockholm, Sweden.
Department of Molecular Medicine and Surgery, Karolinska Institutet, 171 77 Stockholm, Sweden; Department of Craniofacial Surgery, Karolinska University Hospital, 171 76 Stockholm, Sweden.
J Plast Reconstr Aesthet Surg. 2021 Oct;74(10):2479-2485. doi: 10.1016/j.bjps.2021.03.001. Epub 2021 Mar 19.
Free flap complications are generally rare, but not negligible since they may exert paramount impact on both patients and care providers. The aim of the study was to identify risk factors for reexploration and assess predictors associated with increased salvage rates.
A retrospective cohort study was conducted for free flaps performed between 2006 and 2015. Patient demographics, indications and flap types were analyzed together with complications and time to reexploration.
Among 547 consecutive free flaps, 11.5% required acute reexploration. Hematoma together with vascular compromise was the main cause (41.9%) for reexploration, followed by hematoma only (19.4%), venous (16.1%) and arterial (6.5%) thrombosis. Hematoma was associated with an increased risk for concomitant vascular complication (p < 0.02). The incidence of total and partial flap necrosis was 3.5% and 3.7% respectively. There was an overall 71.4% salvage rate. The median time from detection of a compromised flap to reexploration was 3.0 h. Significantly higher salvage rates were observed for cases reexplored within (82.4%) compared to after (57.1%) 3.0 h (OR 3.50 (95% CI 1.10 to 11.13, p = 0.034)).
The current study highlights the importance of early intervention, including evacuation of hematomas that may lead to vascular compromise. Adequate monitoring of venous outflow was found necessary to improve flap salvage rates, whereas arterial complications were mainly related to persistent arterial injury in traumatized extremities with reduced salvage rates. Free flap surgery requires trained staff and immediate access to operating facilities to ensure high flap survival rates.
游离皮瓣并发症通常较为罕见,但也不容忽视,因为它们可能会对患者和医护人员产生重大影响。本研究旨在确定再次探查的风险因素,并评估与提高挽救率相关的预测因素。
对 2006 年至 2015 年期间进行的游离皮瓣进行回顾性队列研究。分析患者人口统计学、适应证和皮瓣类型,以及并发症和再次探查时间。
在 547 例连续游离皮瓣中,11.5%需要进行急性再次探查。血肿合并血管并发症是再次探查的主要原因(41.9%),其次是单纯血肿(19.4%)、静脉(16.1%)和动脉(6.5%)血栓形成。血肿与并发血管并发症的风险增加相关(p<0.02)。总皮瓣坏死和部分皮瓣坏死的发生率分别为 3.5%和 3.7%。总体挽救率为 71.4%。从发现受影响皮瓣到再次探查的中位时间为 3.0 小时。在 3.0 小时内进行再次探查的病例挽救率明显更高(82.4%比 3.0 小时后进行的病例为 57.1%;OR 3.50(95%CI 1.10 至 11.13,p=0.034))。
本研究强调了早期干预的重要性,包括清除可能导致血管并发症的血肿。发现静脉回流不足时,需要进行适当的监测,以提高皮瓣挽救率,而动脉并发症主要与创伤性四肢的动脉持续性损伤有关,挽救率较低。游离皮瓣手术需要训练有素的工作人员和立即获得手术设施,以确保高皮瓣存活率。