Durrington Hannah J, Clark Richard, Greer Ruari, Martial Franck P, Blaikley John, Dark Paul, Lucas Robert J, Ray David W
Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, AV Hill Building, University of Manchester, Manchester, M139PT, UK.
Manchester Emergency and Intensive Care Research Group, Central Manchester Foundation Trust, Oxford Road, Manchester, M139WL, UK.
Intensive Care Med Exp. 2017 Dec;5(1):9. doi: 10.1186/s40635-017-0122-9. Epub 2017 Feb 7.
Intensive care units provide specialised care for critically ill patients around the clock. However, intensive care unit patients have disrupted circadian rhythms. Furthermore, disrupted circadian rhythms are associated with worse outcome. As light is the most powerful 're-setter' of circadian rhythm, we measured light intensity on intensive care unit. Light intensity was low compared to daylight during the 'day'; frequent bright light interruptions occurred over 'night'. These findings are predicted to disrupt circadian rhythms and impair entrainment to external time. Bright lighting during daytime and black out masks at night might help maintain biological rhythms in critically ill patients and improve clinical outcomes.
重症监护病房全天候为重症患者提供专业护理。然而,重症监护病房的患者昼夜节律紊乱。此外,昼夜节律紊乱与更差的预后相关。由于光线是昼夜节律最强大的“重置器”,我们测量了重症监护病房的光照强度。与白天的日光相比,“白天”的光照强度较低;“夜间”频繁出现强光干扰。预计这些结果会扰乱昼夜节律并损害对外部时间的同步。白天明亮照明和夜间遮光面罩可能有助于维持重症患者的生物节律并改善临床结果。