蛋白质中抗磁各向异性的结构起源
Structural origins of diamagnetic anisotropy in proteins.
作者信息
Worcester D L
出版信息
Proc Natl Acad Sci U S A. 1978 Nov;75(11):5475-7. doi: 10.1073/pnas.75.11.5475.
Abstract
Magnetic anisotropy in proteins and polypeptides can be attributed to the diamagnetic anisotropy of the planar peptide bonds. The alpha helix in particular has large anisotropy due to the axial alignment of the peptide bonds. The regular arrangements of the peptide bonds in beta pleated sheet and collagen structures also produce substantial anisotropy, but less than for alpha helix. The anisotropy permits orientation of small structures of these types in magnetic fields of several kilogauss.
摘要
蛋白质和多肽中的磁各向异性可归因于平面肽键的抗磁各向异性。特别是α螺旋，由于肽键的轴向排列而具有较大的各向异性。β折叠片和胶原蛋白结构中肽键的规则排列也会产生相当大的各向异性，但比α螺旋要小。这种各向异性使得这些类型的小结构能够在几千高斯的磁场中取向。
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本文引用的文献
1
ON THE MAGNETIC ASYMMETRY OF MUSCLE FIBERS.论肌纤维的磁不对称性。
Proc Natl Acad Sci U S A. 1958 Jan;44(1):1-4. doi: 10.1073/pnas.44.1.1.
2
Magnetic field effect on the chlorophyll fluorescence in Chlorella.磁场对小球藻叶绿素荧光的影响。
Biochim Biophys Acta. 1971 Mar 2;226(2):486-91. doi: 10.1016/0005-2728(71)90118-6.
3
Magnetic anisotropy and the orientation of retinal rods in a homogeneous magnetic field.均匀磁场中视网膜视杆细胞的磁各向异性与取向
Proc Natl Acad Sci U S A. 1971 Jun;68(6):1283-5. doi: 10.1073/pnas.68.6.1283.
4
Magnetic field induced orientation of photosynthetic systems.磁场诱导光合系统的取向
Biochim Biophys Acta. 1972 Apr 20;267(1):65-79. doi: 10.1016/0005-2728(72)90138-7.
5
[Rotation of external segments of photoreceptors in constant magnetic field].[恒定磁场中光感受器外节的旋转]
C R Acad Hebd Seances Acad Sci D. 1970 Jul 6;271(1):130-3.
6
Orientation of chlorophyll in vivo. Studies with magnetic field oriented chlorella.体内叶绿素的取向。磁场取向小球藻的研究。
Biochem Biophys Res Commun. 1973 Apr 2;51(3):597-602. doi: 10.1016/0006-291x(73)91356-9.
7
The state of chlorophyll and carotenoid in vivo. II. A linear dichroism study of pigment orientation in photosynthetic bacteria.体内叶绿素和类胡萝卜素的状态。II. 光合细菌中色素取向的线性二色性研究。
Biochem Biophys Res Commun. 1974 Aug 5;59(3):1011-7. doi: 10.1016/s0006-291x(74)80080-x.
8
Molecular structure determination by electron microscopy of unstained crystalline specimens.通过电子显微镜对未染色晶体标本进行分子结构测定。
J Mol Biol. 1975 May 25;94(3):425-40. doi: 10.1016/0022-2836(75)90212-0.
9
Three-dimensional model of purple membrane obtained by electron microscopy.通过电子显微镜获得的紫膜三维模型。
Nature. 1975 Sep 4;257(5521):28-32. doi: 10.1038/257028a0.
10
Bacteriorhodospin: a trans-membrane pump containing alpha-helix.细菌视紫红质：一种含有α-螺旋的跨膜泵。
J Mol Biol. 1975 Apr 5;93(2):139-58. doi: 10.1016/0022-2836(75)90124-2.
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