通过电子显微镜获得的紫膜三维模型。

Three-dimensional model of purple membrane obtained by electron microscopy.

作者信息

Henderson R, Unwin P N

出版信息

Nature. 1975 Sep 4;257(5521):28-32. doi: 10.1038/257028a0.

Abstract

A 7-A resolution map of the purple membrane has been obtained by electron microscopy of tilted, unstained specimens. The protein in the membrane contains seven, closely packed, alpha-helical segments which extend roughly perpendicular to the plane of the membrane for most of its width. Lipid bilayer regions fill the spaces between the protein molecules.

摘要

通过对倾斜的未染色标本进行电子显微镜观察，获得了紫膜的7-A分辨率图谱。膜中的蛋白质包含七个紧密排列的α-螺旋片段，这些片段在膜的大部分宽度上大致垂直于膜平面延伸。脂质双层区域填充了蛋白质分子之间的空间。