Hagen Roger, Hjemdal Odin, Solem Stian, Kennair Leif Edward Ottesen, Nordahl Hans M, Fisher Peter, Wells Adrian
Department of Psychology, Norwegian University of Science and Technology Trondheim, Norway.
Institute of Psychology Health and Society, University of Liverpool Liverpool, England.
Front Psychol. 2017 Jan 24;8:31. doi: 10.3389/fpsyg.2017.00031. eCollection 2017.
This randomized controlled trial examines the efficacy of metacognitive therapy (MCT) for depression. Thirty-nine patients with depression were randomly assigned to immediate MCT (10 sessions) or a 10-week wait list period (WL). The WL-group received 10 sessions of MCT after the waiting period. Two participants dropped out from WL and none dropped out of immediate MCT treatment. Participants receiving MCT improved significantly more than the WL group. Large controlled effect sizes were observed for both depressive ( = 2.51) and anxious symptoms ( = 1.92). Approximately 70-80% could be classified as recovered at post-treatment and 6 months follow-up following immediate MCT, whilst 5% of the WL patients recovered during the waiting period. The results suggest that MCT is a promising treatment for depression. Future controlled studies should compare MCT with other active treatments.
这项随机对照试验检验了元认知疗法（MCT）治疗抑郁症的疗效。39名抑郁症患者被随机分配至立即接受MCT（10个疗程）组或10周的等待期（WL）组。等待期组在等待期结束后接受10个疗程的MCT。两名参与者退出了等待期组，立即接受MCT治疗的参与者无人退出。接受MCT治疗的参与者比等待期组改善更为显著。观察到抑郁症状（效应量=2.51）和焦虑症状（效应量=1.92）的对照效应量都很大。立即接受MCT治疗后，约70%-80%的患者在治疗后及6个月随访时可被归类为康复，而等待期组有5%的患者在等待期康复。结果表明，MCT是一种有前景的抑郁症治疗方法。未来的对照研究应将MCT与其他有效治疗方法进行比较。
