围绝经期女性易患抑郁症的相关因素。
Factors associated with the high susceptibility to depression of women during the perimenopause.
机构信息
Department of Psychiatry, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, 510630, P. R. China.
Guangdong Mental Health Center, Guangdong Provincial People's hospital, Guangdong Academy of Medical Sciences, Affiliated School of Medicine of South China University of Technology, Guangzhou, Guangdong Province, 510080, P. R. China.
出版信息
Brain Behav. 2023 Jan;13(1):e2826. doi: 10.1002/brb3.2826. Epub 2022 Dec 8.
OBJECTIVE
This study investigated the factors associated with the high susceptibility of perimenopausal women to depression.
METHODS
A total of 66 perimenopausal women participated in this study. The Zung self-rating depression scale (SDS) was used to evaluate the intensity of depressive symptoms. The modified Kupperman index (KI) was used to assess common perimenopausal symptoms. Psychosocial factors were assessed via the Eysenck Personality Questionnaire, attitudes toward menopause checklist, and metacognition questionnaire (MCQ). Levels of serum estradiol, testosterone, and progesterone were determined.
RESULTS
There were statistically significant associations between SDS standard score and the KI scale score (β = .361, p = .001), years of education (β = -.309, p = .005), and F3 cognitive self-consciousness score of MCQ (β = -.234, p = .032; adjusted R = .264, F = 8.759, p < .001).
CONCLUSIONS
High susceptibility to depression of perimenopausal women may be related to lower educational level, more severe perimenopausal symptoms, and altered metacognition.
目的
本研究旨在探讨围绝经期妇女易患抑郁症的相关因素。
方法
共有 66 名围绝经期妇女参与了本研究。采用zung 自评抑郁量表（SDS）评估抑郁症状的严重程度，采用改良 kupperman 指数（KI）评估常见围绝经期症状。采用艾森克人格问卷、绝经态度检查表和元认知问卷（MCQ）评估心理社会因素。检测血清雌二醇、睾酮和孕酮水平。
结果
SDS 标准分与 KI 量表评分呈显著正相关（β=0.361，p=0.001），与受教育年限（β=-0.309，p=0.005）和 MCQ 的 F3 认知自我意识评分呈显著负相关（β=-0.234，p=0.032；调整后的 R²=0.264，F=8.759，p<0.001）。
结论
围绝经期妇女易患抑郁症可能与受教育程度较低、围绝经期症状更严重和认知改变有关。
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