Hirai Sho, Horikawa Yurie, Asahara Haruyasu, Nishiwaki Nagatoshi
School of Environmental Science and Engineering, Kochi University of Technology, Tosayamada, Kami, Kochi 782-8502, Japan.
Chem Commun (Camb). 2017 Feb 16;53(15):2390-2393. doi: 10.1039/c7cc00051k.
A new method for synthesizing polyalkylated/arylated nicotinates is established using a condensation of enamino esters with enones in the presence of FeCl. This method facilitates the introduction of alkyl or aryl groups at any position on demand, which has not been achieved by other procedures.
一种合成多烷基化/芳基化烟酸酯的新方法得以确立，该方法是在氯化铁存在的情况下，通过烯胺酯与烯酮的缩合反应来实现的。此方法便于根据需要在任何位置引入烷基或芳基，这是其他方法所未能实现的。
