Exploring protein sequence-function landscapes.
作者信息
Starr Tyler N, Thornton Joseph W
机构信息
Graduate Program in Biochemistry and Molecular Biophysics, University of Chicago, Chicago, Illinois, USA.
Departments of Ecology &Evolution and Human Genetics, University of Chicago, Chicago, Illinois, USA.
出版信息
Nat Biotechnol. 2017 Feb 8;35(2):125-126. doi: 10.1038/nbt.3786.
Abstract
摘要
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本文引用的文献
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Epistasis in protein evolution.蛋白质进化中的上位性
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Coevolutionary Landscape Inference and the Context-Dependence of Mutations in Beta-Lactamase TEM-1.β-内酰胺酶TEM-1的协同进化景观推断及突变的上下文依赖性
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Deep mutational scanning: a new style of protein science.深度突变扫描：一种新的蛋白质科学研究方法。
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Should evolutionary geneticists worry about higher-order epistasis?进化遗传学家是否应该担心高阶上位性？
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Emerging methods in protein co-evolution.蛋白质共进化的新兴方法。
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