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艾滋病相关空泡性脊髓病与I型人类嗜T淋巴细胞病毒合并感染无关。

AIDS-related vacuolar myelopathy is not associated with coinfection by human T-lymphotropic virus type I.

作者信息

Brew B J, Hardy W, Zuckerman E, Chien N, Paul M, Rosenblum M, Gadler H, Vahlne A, Gold J, Armstrong D A

机构信息

Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY.

出版信息

Ann Neurol. 1989 Nov;26(5):679-81. doi: 10.1002/ana.410260515.

Abstract

Assessment of antibodies against human T-lymphotropic virus type I (HTLV-I) by enzyme-linked immunoassay, immunofluorescence, and Western blot was undertaken in patients with pathologically or clinically diagnosed acquired immunodeficiency syndrome-related vacuolar myelopathy to determine whether this retrovirus could be etiologically implicated in this disorder. No serological evidence for HTLV-I was found in the patients with vacuolar myelopathy, though 1 patient with an atypical myelopathy did have antibodies against HTLV-I.

摘要

对经病理或临床诊断为获得性免疫缺陷综合征相关空泡性脊髓病的患者,采用酶联免疫吸附测定、免疫荧光和蛋白质免疫印迹法检测抗人嗜T淋巴细胞病毒I型(HTLV-I)抗体,以确定这种逆转录病毒是否在病因上与该疾病有关。空泡性脊髓病患者未发现HTLV-I的血清学证据,不过1例非典型脊髓病患者确实有抗HTLV-I抗体。

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