烯烃的三组分双官能化反应生成β-乙酰氨基硫醚和β-乙酰氧基硫醚。
Three-component difunctionalization of alkenes leading to β-acetamido sulfides and β-acetoxy sulfides.
作者信息
Wang Dingyi, Yan Zhaohua, Xie Qihuang, Zhang Rongxing, Lin Sen, Wang Yuanxing
机构信息
College of Chemistry, Nanchang University, Nanchang, Jiangxi 330031, China.
School of Food Science & Technology, Nanchang University, Nanchang, Jiangxi 330031, China.
出版信息
Org Biomol Chem. 2017 Mar 1;15(9):1998-2002. doi: 10.1039/c7ob00110j.
A novel method for the synthesis of β-acetamido sulfides via NBS-mediated aminosulfenylation of alkenes with thiophenols and nitriles under metal-free conditions has been described. And β-acetamido sulfides were also synthesized with 1-(arylthio)pyrrolidine-2,5-diones as substrates and HBr as an additive. On the other hand, iodine-catalyzed 1,2-acetoxysulfenylation of alkenes by using (diacetoxyiodo)benzene as an oxygen source to synthesise various β-acetoxy sulfides was described as well.
本文描述了一种在无金属条件下，通过N-溴代琥珀酰亚胺（NBS）介导的烯烃与硫酚和腈的氨磺酰化反应合成β-乙酰氨基硫化物的新方法。此外，还以1-（芳硫基）吡咯烷-2,5-二酮为底物、HBr为添加剂合成了β-乙酰氨基硫化物。另一方面，还描述了以（二乙酰氧基碘）苯为氧源，通过碘催化烯烃的1,2-乙酰氧基磺酰化反应合成各种β-乙酰氧基硫化物的方法。
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