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基于吲哚菁绿荧光的投影配准技术实现肝脏手术实时导航:新型医学影像投影系统的研发。

Real-time Navigation for Liver Surgery Using Projection Mapping With Indocyanine Green Fluorescence: Development of the Novel Medical Imaging Projection System.

机构信息

Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Department of Surgery, Hyogo College of Medicine, Hyogo, Japan.

出版信息

Ann Surg. 2018 Jun;267(6):1134-1140. doi: 10.1097/SLA.0000000000002172.

Abstract

OBJECTIVE

The aim of the present study was to evaluate the usefulness of a new imaging device, the Medical Imaging Projection System (MIPS), which uses the indocyanine green emission signal and active projection mapping, for liver resection.

BACKGROUND

During anatomic liver resection, surgeons cannot completely view the intraparenchymal structure. Although a fluorescent imaging technique using indocyanine green has recently been developed for hepatobiliary surgery, limitations in its application for real-time navigation persist.

METHODS

We conducted a retrospective review of surgical and clinical outcomes for 23 patients who underwent anatomic hepatectomy using the MIPS and 29 patients who underwent the procedure without MIPS guidance, between September 2014 and September 2015.

RESULTS

Preoperative characteristics were comparable between the 2 groups. No significant between-group differences were identified with regard to surgical and clinical outcomes. The demarcation lines were clearly projected by the MIPS in 21 patients; however, the boundary line was undetectable in 2 patients.

CONCLUSIONS

We developed the MIPS to address limitations in current intraoperative imaging methods. Our retrospective analysis provides evidence of the feasibility and clinical utility of the MIPS to identify anatomical landmarks for parenchymal dissection. The MIPS holds promise as a novel real-time navigation system for liver resection.

摘要

目的

本研究旨在评估一种新的成像设备——医学成像投影系统(MIPS)在肝切除术中的应用价值。该系统利用吲哚菁绿的发射信号和主动投影映射技术。

背景

在解剖性肝切除术中,外科医生无法完全观察到肝内结构。虽然最近已经开发出一种用于肝胆手术的荧光成像技术,但该技术在实时导航中的应用仍存在局限性。

方法

我们回顾性分析了 2014 年 9 月至 2015 年 9 月期间 23 例行解剖性肝切除术的患者(使用 MIPS 组)和 29 例行该手术但未使用 MIPS 引导的患者(对照组)的手术和临床结果。

结果

两组患者的术前特征具有可比性。两组患者在手术和临床结果方面均无显著差异。MIPS 可在 21 例患者中清晰投射出标记线,但在 2 例患者中无法检测到边界线。

结论

我们开发了 MIPS 以解决当前术中成像方法的局限性。我们的回顾性分析为 MIPS 用于识别肝实质解剖标志提供了可行性和临床应用价值的证据。MIPS 有望成为一种新的实时肝切除术导航系统。

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