Brusilovskiĭ A I, Shapovalova E Iu
Arkh Anat Gistol Embriol. 1989 Jul;97(7):32-9.
In 50 human embryos, distributed according to the age scale from the 21st day up to 12 weeks of the intrauterine development, which includes stages X-XXIII and beginning of the fetal period (classification of Carnegie Institute), the diameter and volume of the cell nuclei have been followed in the process of formation of epithelial and mesenchymal derivatives of the eye accessory apparatus. In early histogenesis of the eye accessory apparatus the dimensions of the cell nuclei of all epithelial and mesenchymal anlages decrease linearly. In the cells of the epithelial derivatives decrease of the nuclear dimensions in expressed more significantly than the mesenchymal ones. The dynamics of the nuclear dimensions is compared with the form of the same nuclei in each anlage. The nuclear form changes. The differentiation in all the anlages occurs similarly: cells with nuclei having various size appear. Each tissue by the moment, when it appears from the tissue source, possesses cells with nuclei, significantly differing from the nuclei in the latter. In accordance with the modern cytological data, problems and matters making the base of the changes in the nuclei in the course of embryonal histogenesis are discussed.
在50个人类胚胎中，这些胚胎根据子宫内发育从第21天到12周的年龄尺度分布，涵盖卡内基研究所分类中的X - XXIII阶段以及胎儿期开始阶段，研究了眼附属器上皮和间充质衍生物形成过程中细胞核的直径和体积。在眼附属器的早期组织发生过程中，所有上皮和间充质原基的细胞核尺寸呈线性减小。在上皮衍生物的细胞中，核尺寸的减小比间充质细胞更为显著。将核尺寸的动态变化与每个原基中相同细胞核的形态进行比较。核形态发生变化。所有原基中的分化过程相似：出现了具有不同大小细胞核的细胞。每个组织从组织源出现时，其拥有的细胞核与后者的细胞核显著不同。根据现代细胞学数据，讨论了胚胎组织发生过程中细胞核变化的基础问题。
