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[大鼠产前发育期间肺组织的核测量特征]

[The karyometric characteristics of rat lung tissue during prenatal development].

作者信息

Sluka B A

出版信息

Morfologiia. 1993 Jan-Feb;104(1-2):85-93.

PMID:8293136
Abstract

The embryonic histogenesis of tissues of mesenchymal and epithelial origin was studied in the lungs of 150 embryos of the Albino rat (from 10 to 21 days of development) by methods of morphometry. Two phases in the dynamics of the nucleus form factor were established. The first phase (10-14 days) coincides with processes of programming and determination of the cells and is completed by a separation of the muscular, connective and cartilaginous tissues from the common mesenchymal germ. The second phase (16-21 days) is characterized by the divergent development of mesenchymal derivatives and demonstrates processes of cytodifferentiation and specialization of the cells. The appearance of heterogeneity of the cell forms leads to a growth of entropy of tissue anlagen. The restriction of the entropy is achieved by the integration of structures resulting from the formation of the system of correlation connections. Their amount first grows, and when specialization begins it becomes less.

摘要

采用形态计量学方法,对150只白化大鼠胚胎(发育10至21天)肺脏中源自间充质和上皮组织的胚胎组织发生进行了研究。确定了核形态因子动态变化的两个阶段。第一阶段(10 - 14天)与细胞编程和决定过程相吻合,并以肌肉、结缔组织和软骨组织从共同的间充质胚层分离而结束。第二阶段(16 - 21天)的特征是间充质衍生物的分化发育,并显示出细胞的细胞分化和特化过程。细胞形态异质性的出现导致组织原基熵的增加。熵的限制是通过相关连接系统形成所产生结构的整合来实现的。其数量首先增加,而当特化开始时则减少。

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