Fiore P M, Richter C U, Arzeno G, Arrigg C A, Shingleton B J, Bellows A R, Hutchinson B T
Glaucoma Consultation Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Mass.
Arch Ophthalmol. 1989 Nov;107(11):1609-11. doi: 10.1001/archopht.1989.01070020687028.
Eighteen patients undergoing glaucoma filtration surgery underwent specular microscopic examination 1 day prior to surgery and 4 to 6 months after surgery. Patients were evaluated postoperatively for the presence of iridocorneal or lenticular-corneal touch, anterior chamber depth, and inflammation. Ten eyes that maintained their anterior chamber following glaucoma filtration surgery did not have a significant decrease in corneal endothelial cell density. However, eight eyes that developed a shallow anterior chamber with iridocorneal touch had a mean (+/- SD) decrease of 265 +/- 185 cells (12.4%) peripherally and 250 +/- 243 cells (11.6%) centrally in corneal endothelial cell count. None of the patients with iridocorneal touch developed corneal edema after a mean follow-up of 44.4 +/- 18.0 months. Iridocorneal touch after glaucoma filtration surgery is associated with loss of endothelial cells yet appears to be well tolerated by the cornea.
18例接受青光眼滤过手术的患者在手术前1天以及术后4至6个月接受了镜面显微镜检查。术后对患者进行虹膜角膜或晶状体角膜接触、前房深度和炎症情况的评估。青光眼滤过手术后前房得以维持的10只眼中，角膜内皮细胞密度没有显著下降。然而，8只出现前房变浅并伴有虹膜角膜接触的眼睛，角膜内皮细胞计数周边平均（±标准差）减少265±185个细胞（12.4%），中央减少250±243个细胞（11.6%）。平均随访44.4±18.0个月后，所有伴有虹膜角膜接触的患者均未发生角膜水肿。青光眼滤过手术后的虹膜角膜接触与内皮细胞丢失有关，但角膜似乎对此耐受性良好。
