Center for Interdisciplinary Research, D. Y. Patil University, Kolhapur 416006, Maharashtra, India.
Center for Interdisciplinary Research, D. Y. Patil University, Kolhapur 416006, Maharashtra, India.
Mater Sci Eng C Mater Biol Appl. 2017 Apr 1;73:257-266. doi: 10.1016/j.msec.2016.12.043. Epub 2016 Dec 13.
Initially micro-organisms get exposed to the surfaces, this demands development of anti-microbial surfaces to inhibit their proliferation. Therefore, herein, we attempt screen printing technique for development of PVA-GE/ZnO nanocomposite (PG/ZnO) films. The synthesis of PG/ZnO nanocomposite includes two steps as: (i) Coating of Zinc Oxide nanoparticles (ZnO NPs) by poly ethylene glycol in order to be compatible with organic counterparts. (ii) Deposition of coated nanoparticles on the PG film surface. The results suggest the enhancement in anti-microbial activity of PG/ZnO nanocomposite over pure ZnO NPs against both Gram positive Bacillus subtilis and Gram negative Escherichia coli from zone of inhibition. The uniformity in deposition is further confirmed by scanning electron microscopy (SEM) images. The phase identification of ZnO NPs and formation of PG/ZnO nanocomposite has been confirmed by X-ray diffraction (XRD) analysis and UV-vis spectroscopy (UV-vis). The Attenuated total reflection Spectroscopy (ATR) analysis indicates the ester bond between PVA and gelatin molecules. The thermal stability of nanocomposite is studied by thermogravimetric analysis (TGA) revealing increase in crystallinity due to ZnO NPs which could be utilized to inhibit the growth of micro-organisms. The tensile strength is found to be higher and percent elongation is double of PG/ZnO nanocomposite than PG composite film.
最初，微生物会暴露在表面，这就需要开发抗菌表面来抑制其增殖。因此，本文尝试采用丝网印刷技术来制备 PVA-GE/ZnO 纳米复合材料（PG/ZnO）薄膜。PG/ZnO 纳米复合材料的合成包括两个步骤：（i）用聚乙二醇对氧化锌纳米粒子（ZnO NPs）进行包覆，以使其与有机物质相容。（ii）将包覆后的纳米粒子沉积在 PG 膜表面。结果表明，与纯 ZnO NPs 相比，PG/ZnO 纳米复合材料对革兰氏阳性枯草芽孢杆菌和革兰氏阴性大肠杆菌的抑菌活性均有所增强。从抑菌圈的结果可以看出沉积的均匀性。通过扫描电子显微镜（SEM）图像进一步证实了这一点。通过 X 射线衍射（XRD）分析和紫外可见光谱（UV-vis）证实了 ZnO NPs 的相鉴定和 PG/ZnO 纳米复合材料的形成。衰减全反射光谱（ATR）分析表明 PVA 和明胶分子之间存在酯键。通过热重分析（TGA）研究了纳米复合材料的热稳定性，结果表明由于 ZnO NPs 的存在，结晶度增加，这可以用来抑制微生物的生长。与 PG 复合膜相比，PG/ZnO 纳米复合材料的拉伸强度更高，伸长率是其两倍。
