Tran Arthur-Quan, Gehrig Paola
Gynecologic Oncology, University of North Carolina at Chapel Hill, NC, USA.
F1000Res. 2017 Jan 27;6:81. doi: 10.12688/f1000research.10020.1. eCollection 2017.
Endometrial cancer is the most common gynecologic malignancy in the United States, with yearly rates continuing to increase. Most women present with early stage disease; however, advanced disease carries a grave prognosis. As a result, novel therapies are currently under investigation for the treatment of endometrial cancer. These advances include a better understanding of the genetic basis surrounding the development of endometrial cancer, novel surgical therapies, and new molecular targets for the treatment of this disease. This review explores the literature regarding these advancements in endometrial cancer.
子宫内膜癌是美国最常见的妇科恶性肿瘤，其年发病率持续上升。大多数女性表现为早期疾病；然而，晚期疾病的预后很差。因此，目前正在研究用于治疗子宫内膜癌的新疗法。这些进展包括对子宫内膜癌发生的遗传基础有了更好的理解、新的手术疗法以及治疗该疾病的新分子靶点。本综述探讨了有关子宫内膜癌这些进展的文献。
