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中国高龄老人的饮食习惯与认知障碍风险。

Dietary Habits and Cognitive Impairment Risk Among Oldest-Old Chinese.

机构信息

Department of Kinesiology and Community Health, College of Applied Health Sciences, University of Illinois at Urbana-Champaign.

China Center for Health Economic Research, National School of Development, Peking University, Beijing, China.

出版信息

J Gerontol B Psychol Sci Soc Sci. 2019 Feb 15;74(3):474-483. doi: 10.1093/geronb/gbw170.

Abstract

OBJECTIVES

This study examined the longitudinal relationship between dietary habits and cognitive impairment among the oldest-old Chinese.

METHOD

Cognitively intact adults aged 80 or older (N = 4,749) came from the Chinese Longitudinal Healthy Longevity Survey. Cognitive impairment was assessed by Mini-mental State Examination. Cox regressions were performed to examine the relationship between dietary habits and cognitive impairment onset during follow-up period of 1998-2012, adjusting for various time-variant and time-invariant individual characteristics.

RESULTS

Compared with those who rarely/never consumed fruit, vegetables, meat, and soybean-derived products, participants consuming such products almost every day were 21%, 25%, 17%, and 20% less likely to develop cognitive impairment during follow-up, respectively. Compared with those who rarely/never consumed sugar, participants consuming sugar almost every day were 17% more likely to develop cognitive impairment during follow-up. Consumption of fish, egg, salt-preserved vegetable, tea, and garlic was not found to be associated with cognitive impairment.

DISCUSSION

Dietary habits might profoundly impact cognitive functioning among the oldest-old Chinese. This work has limitations pertaining to study design and measure. Future work adopting experimental design and refined dietary measures is warranted to confirm these findings and inform public nutrition practices aiming at preventing cognitive decline among the oldest-old Chinese population.

摘要

目的

本研究旨在探讨饮食习惯与中国高龄老人认知障碍之间的纵向关系。

方法

认知正常的 80 岁及以上成年人(N=4749)来自中国长寿纵向研究。认知障碍通过简易精神状态检查进行评估。采用 Cox 回归分析,调整各种随时间变化和随时间不变的个体特征,在 1998 年至 2012 年的随访期间,研究饮食习惯与认知障碍发病之间的关系。

结果

与很少/从不食用水果、蔬菜、肉类和大豆制品的参与者相比,每天几乎都食用这些食物的参与者在随访期间发生认知障碍的风险分别降低了 21%、25%、17%和 20%。与很少/从不食用糖的参与者相比,每天几乎都食用糖的参与者在随访期间发生认知障碍的风险增加了 17%。食用鱼、蛋、腌菜、茶和大蒜与认知障碍无关。

讨论

饮食习惯可能对中国高龄老人的认知功能有深远影响。本研究存在研究设计和测量方面的局限性。未来采用实验设计和更精细的饮食测量方法的研究工作,有助于证实这些发现,并为旨在预防中国高龄老年人群认知能力下降的公共营养实践提供信息。

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