Daftary D K, Pitkar V K, Gupta P C, Pindborg J J, Metha F S
Acta Odontol Scand. 1978;36(6):327-31. doi: 10.3109/00016357809029083.
A preleukoplakia, conceived as a precursor stage of leukoplakia, is grey or greyish-white area with indistinct borders. The paper describes 659 preleukoplakias detected among 20,358 individuals in two districts in India. In Bhavnagar district 99.5% of the preleukoplakias were among men. 23.5% of the hookli (clay pipe) smokers had preleukoplakias. In Ernakulam district 79.6% of the preleukoplakias were found among men and the mixed habit group of bidi smoking and tobacco chewing had the highest prevalence (6.1%). The preleukoplakias showed a marked tendency to regress; among the bidi smokers in Bhavnagar, 75% regressed. In two patients preleukoplakia turned into carcinoma.
白斑前期被认为是白斑的前驱阶段，表现为边界不清的灰色或灰白色区域。该论文描述了在印度两个地区的20358名个体中检测到的659例白斑前期病例。在巴夫那加尔区，99.5%的白斑前期病例发生在男性中。23.5%的水烟（陶土烟斗）吸烟者有白斑前期病变。在埃纳库拉姆区，79.6%的白斑前期病例发生在男性中，而混合有比迪烟吸烟和嚼烟习惯的人群患病率最高（6.1%）。白斑前期病变有明显的消退倾向；在巴夫那加尔的比迪烟吸烟者中，75%的病变消退了。有两名患者的白斑前期病变转变为癌。
