Mitrovic D R, Darmon N, Barbara A, Riera H, Bardin T
INSERM, Department of Rheumatology, Hôpital Lariboisière, Paris, France.
Arthritis Rheum. 1989 Nov;32(11):1477-83. doi: 10.1002/anr.1780321120.
We describe a patient undergoing long-term hemodialysis, in whom severe chondrolysis of the hip joint developed. The chondrolysis evolved in the absence of synovial inflammation and articular chondrocalcinosis. Biochemical studies of articular cartilage retained at surgery revealed deposition of exclusively small proteoglycans in the matrix. This may have been an important factor leading to the rapid chondrolysis in this patient.
我们描述了一名正在接受长期血液透析的患者，该患者出现了严重的髋关节软骨溶解。软骨溶解在没有滑膜炎症和关节软骨钙质沉着的情况下发展。对手术中保留的关节软骨进行的生化研究显示，基质中仅沉积了小蛋白聚糖。这可能是导致该患者软骨迅速溶解的一个重要因素。
