Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Austria.
Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria.
Med Phys. 2017 May;44(5):1638-1645. doi: 10.1002/mp.12150. Epub 2017 Apr 12.
Inspection and quantitative validation of tomographic imaging properties of SPECT systems, i.e., spatial resolution, contrast, and inhomogeneity must be performed in regular intervals. Typically, the modular Jaszczak phantom is used for that purpose, as it offers the possibility to investigate all three system properties with a single measurement. The interpretation of the measurement is performed visually, thus, being insensitive to subtle changes in system performance. To overcome this limitation, a fully-automated software for the objective analysis of Jaszczak phantom measurements is proposed here.
The software was developed as an ImageJ plugin and offers a number of sequential evaluation steps: automatic determination of the type of Jaszczak phantom, calculation of sector and sphere contrast, detection of ring artifacts using either the Hough transform, followed by a threshold-based decision criterion, or Student's t-test. Monte Carlo simulations were used to estimate the detectability limits for ring artifacts.
The software successfully calculated sector and sphere contrasts and reliably determined ring artifacts present in the homogeneity part of the Jaszczak phantom, based on automatic identification of the phantom type.
Given the quantitative nature of the produced output, results from one imaging system can easily be compared to another in an objective way. The advantage of the software is clearly that the information provided is objective and does not rely on the experience level of the user.
必须定期检查和定量验证 SPECT 系统的断层成像特性,即空间分辨率、对比度和非均匀性。通常,使用模块化的 Jaszczak 体模来实现这一目的,因为它可以通过单次测量来研究所有三种系统特性。测量的解释是通过视觉进行的,因此,对系统性能的细微变化不敏感。为了克服这一限制,本文提出了一种用于客观分析 Jaszczak 体模测量的全自动软件。
该软件作为一个 ImageJ 插件开发,提供了一系列连续的评估步骤:自动确定 Jaszczak 体模的类型,计算扇区和球体对比度,使用 Hough 变换或基于学生 t 检验的决策准则检测环形伪影。使用蒙特卡罗模拟来估计环形伪影的检测极限。
该软件成功地计算了扇区和球体对比度,并根据体模类型的自动识别,可靠地确定了 Jaszczak 体模均匀性部分存在的环形伪影。
鉴于产生的输出具有定量性质,很容易以客观的方式比较一个成像系统的结果与另一个系统的结果。该软件的优势在于,提供的信息是客观的,不依赖于用户的经验水平。