Department of Chemistry, Graduate University of Advanced Technology, Kerman, Iran.
Institute of Nano Science and Nano Technology, University of Kashan, Kashan, P.O. Box 87317-51167, Iran.
J Colloid Interface Sci. 2017 Jun 1;495:61-67. doi: 10.1016/j.jcis.2017.01.119. Epub 2017 Feb 3.
In the present work, CuO nanoparticle decorated on single wall carbon nanotubes (CuO/SWCNTs) nanocomposite was successfully synthesized by chemical precipitation method and used for modification of carbon paste electrode (CPE) in the presence of 1-butyl-3-methylimidazolium hexafluorophosphate (1-B-3-MIHFP) liquid as binder. The novel voltammetric sensor was used as first electrochemical sensor for determination of sulfisoxazole (SFX). CuO/SWCNTs nanocomposite characterized by scanning electron microscopy (SEM) and X-ray powder diffraction (XRD) methods. Voltammetric methods such as cyclic voltammetry, square wave voltammetry (SWV), electrochemical impedance spectroscopy (EIS) and chronoamperometry were performed to assess the electrochemical performance of CuO/SWCNTs/1-B-3-MIHFP/CPE towards SFX in aqueous solution. The voltammetric obtained data confirm the significant enhancement of oxidation current and reduction overvoltage for electro-oxidation of SFX at a surface of CuO/SWCNTs/1-B-3-MIHFP/CPE. The square wave voltammetric response shows the linear increment of oxidation signals with an increase in the concentration of SFX in the range of 0.08-650μM with limit of detection 0.04μM. Using CuO/SWCNTs/1-B-3-MIHFP/CPE the SFX and folic acid peaks are separated ca. 0.72 and 0.895V, respectively; hence SFX can be detected in the presence of folic acid. Finally, the CuO/SWCNTs/1-B-3-MIHFP/CPE was used as high sensitive tools for analysis of SFX and folic acid in real samples.
在本工作中，通过化学沉淀法成功合成了氧化铜纳米粒子修饰的单壁碳纳米管（CuO/SWCNTs）纳米复合材料，并将其用于在 1-丁基-3-甲基咪唑六氟磷酸盐（1-B-3-MIHFP）液体存在下修饰碳糊电极（CPE）。该新型伏安传感器首次被用作测定磺胺异噁唑（SFX）的电化学传感器。采用扫描电子显微镜（SEM）和 X 射线粉末衍射（XRD）方法对 CuO/SWCNTs 纳米复合材料进行了表征。采用循环伏安法、方波伏安法（SWV）、电化学阻抗谱（EIS）和计时电流法等伏安法评估了 CuO/SWCNTs/1-B-3-MIHFP/CPE 在水溶液中对 SFX 的电化学性能。伏安法获得的数据证实，在 CuO/SWCNTs/1-B-3-MIHFP/CPE 表面，SFX 的氧化电流和还原过电压显著增强。方波伏安响应显示，随着 SFX 浓度在 0.08-650μM 范围内的增加，氧化信号呈线性增加，检出限为 0.04μM。使用 CuO/SWCNTs/1-B-3-MIHFP/CPE，SFX 和叶酸的峰分别在约 0.72 和 0.895V 处分离；因此，SFX 可以在叶酸存在下进行检测。最后，将 CuO/SWCNTs/1-B-3-MIHFP/CPE 用于分析实际样品中的 SFX 和叶酸。
