CIRI, Centre International de Recherche en Infectiologie, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, École Normale Supérieure de Lyon, Univ Lyon, 69100, Villeurbanne, France.
Department of Biochemistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Trends Microbiol. 2017 Apr;25(4):247-249. doi: 10.1016/j.tim.2017.01.006. Epub 2017 Feb 9.
The stability and function of regulatory small RNAs (sRNAs) often require a specialized RNA-binding protein called an RNA chaperone. Recent findings show that proteins containing a ProQ/FinO domain constitute a new class of RNA chaperones that could play key roles in post-transcriptional gene regulation throughout bacterial species.
调控小 RNA（sRNA）的稳定性和功能通常需要一种称为 RNA 伴侣的特殊 RNA 结合蛋白。最近的研究发现，含有 ProQ/FinO 结构域的蛋白质构成了一类新的 RNA 伴侣，它们可能在细菌物种的转录后基因调控中发挥关键作用。
