新生儿期与非新生儿期法洛四联症的完全修复：一项荟萃分析
Complete Repair of Tetralogy of Fallot in the Neonatal Versus Non-neonatal Period: A Meta-analysis.
作者信息
Loomba Rohit S, Buelow Matthew W, Woods Ronald K
机构信息
Division of Cardiology and Cardiothoracic Surgery, Children's Hospital of Wisconsin/ Medical College of Wisconsin, 9000 Wisconsin Avenue, Milwaukee, WI, 53226, USA.
出版信息
Pediatr Cardiol. 2017 Jun;38(5):893-901. doi: 10.1007/s00246-017-1579-8. Epub 2017 Feb 11.
It is unclear if neonatal tetralogy of Fallot repair offers better outcomes compared to repair later in infancy. We therefore conducted a meta-analysis comparing outcomes of neonatal and non-neonatal repair. Manuscripts were identified and reviewed for quality and bias with favorably scored manuscripts being included in the final meta-analysis. Several perioperative and postoperative variables were compared. A total of 8 studies with 3858 patients were included in the analysis. Of these patients, 19% underwent neonatal repair. Neonatal repair was associated with increased mortality, longer intensive care unit stays, and longer total hospital length of stay.
与婴儿期后期进行法洛四联症修复相比，新生儿期进行该修复是否能带来更好的结果尚不清楚。因此，我们进行了一项荟萃分析，比较新生儿期和非新生儿期修复的结果。我们识别并审查了相关手稿的质量和偏差情况，得分良好的手稿被纳入最终的荟萃分析。我们比较了几个围手术期和术后变量。分析共纳入了8项研究，涉及3858名患者。在这些患者中，19%接受了新生儿期修复。新生儿期修复与死亡率增加、重症监护病房住院时间延长以及总住院时间延长有关。
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