Yoshino Mizuki, Sasaki Jun, Kuramochi Konomi, Ikezawa Mitsutaka, Mukaizawa Natsuko, Goryo Masanobu
Department of Veterinary Pathology, Faculty of Agriculture, Iwate University, Ueda 3-18-8, Morioka, Iwate 020-8550, Japan.
J Vet Med Sci. 2017 Mar 23;79(3):584-587. doi: 10.1292/jvms.16-0515. Epub 2017 Feb 11.
In September 2012, five Bolivian squirrel monkeys housed in a zoological park died within sequential several days without obvious clinical signs. In a necrospy, one monkey presented swelling of the kidney with multifocal white nodules in the parenchyma, and other two had pulmonary congestion. Histopathologically, multifocal bacterial colonies of gram-negative coccobacillus were found in the sinusoid of the liver in all monkeys examined (Nos.1-4). Additionally, purulent pyelonephritis, pneumonia and disseminated small bacterial colonies in blood vessels were observed. Immunohistochemically, the bacterial colonies from two monkeys were positive for P. multocida capsular serotype D. Based on these findings, these monkeys were diagnosed as septicemia caused by acute P. multocida infection.
2012年9月，某动物园饲养的5只玻利维亚松鼠猴在连续几天内死亡，无明显临床症状。尸检时，1只猴子肾脏肿大，实质内有多处白色结节，另外2只出现肺充血。组织病理学检查发现，所有接受检查的猴子（1 - 4号）肝脏血窦内有多处革兰氏阴性球杆菌菌落。此外，还观察到化脓性肾盂肾炎、肺炎以及血管内弥漫性小细菌菌落。免疫组化显示，2只猴子的细菌菌落对多杀性巴氏杆菌荚膜血清型D呈阳性反应。基于这些发现，这些猴子被诊断为急性多杀性巴氏杆菌感染引起的败血症。
