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宫颈长度测量:经腹与经阴道途径的比较

Cervical length measurement: Comparison of transabdominal and transvaginal approach.

作者信息

Westerway Susan Campbell, Pedersen Lars Henning, Hyett Jon

机构信息

Northern Women's ImagingSydneyNew South WalesAustralia; Discipline of Obstetrics Gynaecology and NeonatologyFaculty of MedicineUniversity of SydneySydneyNew South WalesAustralia.

Department of Obstetrics and GynaecologyInstitute of Clinical MedicineAarhus UniversityAarhusDenmark; RPA Women and BabiesRoyal Prince Alfred HospitalSydneyNew South WalesAustralia.

出版信息

Australas J Ultrasound Med. 2015 Feb;18(1):19-26. doi: 10.1002/j.2205-0140.2015.tb00019.x. Epub 2015 Dec 31.

Abstract

: To compare transabdominal (TA) and transvaginal (TV) ultrasound assessment of cervical length at 16-41 weeks gestation. : TA and TV ultrasound measurements of cervical length were made on 491 pregnancies of 16-41 weeks gestation. Cervical length was measured from internal to external cervical os. Bland-Altman plots and Wilcoxon signed rank test were used to evaluate differences between TA and TV measurements. : The validity of the TA method depended on cervical length. Although the TA method underestimated cervical length by 2.0 mm on average ( < 0.001), Bland Altman plots showed an inverse trend with shorter cervixes. In women with a cervix < 25 mm (n = 30) based on TV scan measurement, TA overestimated cervical length by 12 mm (P < 0.001). The sensitivity and specificity of TA as a test to detect cervical length < 25 mm were 10% (95% CI: 2.1-26%) and 94% (95% CI: 92-96%) respectively; the negative LR was 0.96 (95% CI: 0.84-1.08). The maximum area under the ROC curve would be obtained at a TA cut-off = 32 mm (to detect a cervix < 25 mm), corresponding to a sensitivity of 77% and a specificity of 58%. : TA measurements do not reflect TV assessment accurately, particularly if the cervix is short. At 24-34 weeks, a policy of proceeding to TV scan if TA measurement is < 25 mm will only detect 10% of affected pregnancies and has a poor positive predictive value so is of limited value as a predictive tool for women attending with symptoms and signs of preterm labour > 24 weeks gestation. There is no value in TA assessment of the cervix > 36 weeks.

摘要

比较孕16 - 41周经腹(TA)和经阴道(TV)超声测量宫颈长度的情况。对491例孕16 - 41周的孕妇进行TA和TV超声测量宫颈长度。宫颈长度从宫颈内口测量至外口。采用Bland - Altman图和Wilcoxon符号秩检验评估TA和TV测量值之间的差异。TA测量方法的有效性取决于宫颈长度。虽然TA测量方法平均低估宫颈长度2.0毫米(P < 0.001),但Bland - Altman图显示宫颈越短差异越大。对于经TV扫描测量宫颈长度< 25毫米的女性(n = 30),TA测量值高估宫颈长度12毫米(P < 0.001)。TA检测宫颈长度< 25毫米的敏感度和特异度分别为10%(95%可信区间:2.1 - 26%)和94%(95%可信区间:92 - 96%);阴性似然比为0.96(95%可信区间:0.84 - 1.08)。当TA测量值截断点为32毫米时(用于检测宫颈长度< 25毫米),ROC曲线下最大面积对应的敏感度为77%,特异度为58%。TA测量不能准确反映TV评估结果,尤其是宫颈较短时。在孕24 - 34周,如果TA测量值< 25毫米就进行TV扫描的策略只能检测出10%的受影响妊娠,且阳性预测值较差,因此作为孕周> 24周出现早产症状和体征的孕妇的预测工具价值有限。孕36周后TA评估宫颈无价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d21/5024954/31bb7f414efa/AJUM-18-19-g001.jpg

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