Division of Gastroenterology, University of Colorado School of Medicine, Aurora, Colorado.
Division of Gastroenterology, University of Colorado School of Medicine, Aurora, Colorado.
Gastroenterology. 2017 May;152(7):1791-1801. doi: 10.1053/j.gastro.2017.01.044. Epub 2017 Feb 10.
Endoscopic bariatric and metabolic therapies (EBMT) are a new addition to the treatment arsenal for obesity. These include devices that are placed or removed via flexible endoscopy, and procedures that utilize instruments that require flexible endoscopy for the indications of weight loss or treatment of glucose intolerance (from pre-diabetes to diabetes). The EBMTs are generally divided into gastric and small bowel categories, and although individual EBMTs may have unique mechanisms of action, similar themes in proposed mechanism of action are seen in the gastric and small bowel EBMTs, respectively. In this review we will describe the therapies approved for use in the United States or currently in the process of obtaining approval for use in the United States. We will discuss potential mechanisms of action and examine safety and efficacy data.
内镜减重与代谢治疗（Endoscopic Bariatric and Metabolic Therapies，EBMT）是肥胖症治疗手段中的一种新方法。这些方法包括通过软性内镜来放置或移除的设备，以及需要软性内镜来进行减重或治疗葡萄糖不耐受（从糖尿病前期到糖尿病）的操作。EBMT 通常分为胃和小肠两类，尽管每种 EBMT 可能具有独特的作用机制，但在胃和小肠 EBMT 中可以看到类似的作用机制主题。在本综述中，我们将描述已在美国获得批准使用或正在获得美国批准的治疗方法。我们将讨论潜在的作用机制，并检查安全性和疗效数据。
