HPV 疫苗接种启动不足的原因：从性别和性取向转移到必要性和安全性。
Reasons for Lack of HPV Vaccine Initiation in NIS-Teen Over Time: Shifting the Focus From Gender and Sexuality to Necessity and Safety.
机构信息
The Kelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics, Johns Hopkins Medicine, Baltimore, Maryland.
Cancer Prevention Fellowship Program, National Cancer Institute, Bethesda, Maryland.
出版信息
J Adolesc Health. 2018 Nov;63(5):652-656. doi: 10.1016/j.jadohealth.2018.06.024.
PURPOSE
To describe changes in parents' reasons for lack of HPV vaccine initiation in American male and female adolescents from 2010 to 2016.
METHODS
Log binomial regression was used to examine prevalence and trends across time in reasons parents do not intend to vaccinate from the National Immunization Survey - Teen (NIS-Teen).
RESULTS
In females, safety concerns were the most common reasons in 2010 (23%) and 2016 (22%). Lack of necessity (21% vs. 20%), knowledge (14% vs. 13%), and recommendation (9% vs. 10.0%) remained stable, whereas child's lack of sexual activity decreased from 19% to 10% (p<.01). For males, lack of necessity (24% vs. 22%), recommendation (22% vs. 17%), and knowledge (16% vs. 14%), and child's lack of sexual activity (16% vs. 9%) and gender (13% vs. 2%) decreased from 2010 to 2016 (p<.05). Safety concerns increased (5% vs. 14%) (p<.01).
CONCLUSIONS
Vaccine messages should reflect current trends and focus on persistent concerns about knowledge, safety, and necessity, rather than sexuality and gender.
目的
描述 2010 年至 2016 年期间美国男、女青少年家长因缺乏 HPV 疫苗接种而缺乏疫苗接种的原因的变化。
方法
使用对数二项式回归来检查国家免疫调查-青少年（NIS-Teen）中父母不打算接种疫苗的原因在时间上的流行率和趋势。
结果
在女性中，2010 年（23%）和 2016 年（22%）安全问题是最常见的原因。缺乏必要性（21%比 20%）、知识（14%比 13%）和推荐（9%比 10.0%）保持稳定，而儿童缺乏性活动从 19%下降到 10%（p<.01）。对于男性，缺乏必要性（24%比 22%）、推荐（22%比 17%）和知识（16%比 14%）以及儿童缺乏性活动（16%比 9%）和性别（13%比 2%）从 2010 年下降到 2016 年（p<.05）。安全问题增加（5%比 14%）（p<.01）。
结论
疫苗信息应反映当前趋势，并侧重于持续关注知识、安全性和必要性方面的问题，而不是性和性别方面的问题。
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