慢性精神分裂症患者日间体重增加及尿量的调查

Survey of diurnal weight gain and urine volume in chronic schizophrenia.

作者信息

Vieweg W V, Godleski L S, Hundley P L, Yank G R

机构信息

Department of Mental Health and Mental State Hospital, Staunton, VA 24401.

出版信息

Can J Psychiatry. 1989 Nov;34(8):779-84. doi: 10.1177/070674378903400807.

DOI:10.1177/070674378903400807

PMID:2819641

Abstract

We found diurnal weight gain to be abnormal among 39 chronic schizophrenic patients. The patients were weighed and urine samples obtained weekly for three weeks at 7 a.m. and 4 p.m. We normalized the dirunal weight gain (NDWG) as a percentage by subtracting the 7 a.m. weight from the 4 p.m. weight, multiplying the difference by 100, and then dividing the result by the 7 a.m. weight. NDWG was 2.075 +/- 1.331% for the 38 study patients, .631 +/- .405% for 16 acutely psychotic controls and .511 +/- .351% for 29 normals. Seventy-seven percent of the study patients had abnormal NDWG values and 62% were polyuric. NDWG related to urine volume (n = 39, r = .356, p = .026) with the variability in urine excretion explaining 13% of the variability in NDWG. We discuss factors that may have contributed to our findings.

摘要

我们发现39名慢性精神分裂症患者的日间体重增加异常。在三周的时间里，每周上午7点和下午4点对患者进行称重并采集尿液样本。我们通过以下方式将日间体重增加（NDWG）标准化为百分比：用下午4点的体重减去上午7点的体重，将差值乘以100，然后将结果除以上午7点的体重。38名研究患者的NDWG为2.075±1.331%，16名急性精神病对照组患者为0.631±0.405%，29名正常人则为0.511±0.351%。77%的研究患者NDWG值异常，62%的患者多尿。NDWG与尿量相关（n = 39，r = 0.356，p = 0.026），尿液排泄的变异性解释了NDWG变异性的13%。我们讨论了可能导致我们研究结果的因素。