Montazerifar Farzaneh, Bolouri Ahmad, Mahmoudi Mozaffar Milad, Karajibani Mansour
Pregnancy Health Research Center, Department of Nutrition, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Department of Cardiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Cardiol Res. 2016 Dec;7(6):202-208. doi: 10.14740/cr507w. Epub 2016 Dec 31.
Metabolic syndrome (MetS) is a worldwide health problem, which is growing in Iranian adults. MetS is associated with risk of type 2 diabetes and coronary artery disease (CAD). In this study, we aimed to investigate the prevalence of MetS and its individual components in CAD patients.
This cross-sectional study was performed on 200 CAD patients who had undergone elective coronary angiography at the cardiology department. Anthropometric indices including waist circumference (WC) and body mass index were measured. Blood samples were obtained to determine glucose and lipid profile. MetS components were defined according to the modified Adult Treatment Panel III (ATP III) criteria.
The prevalence of MetS among patients was 49.5% (women: 55.9%; men: 40.2%; P < 0.05). The prevalence increased with age. The low high-density lipoprotein-cholesterol (low HDL-C) (84.8%), high fasting blood glucose (high FBG) (77.8%) and high WC (75.8%) were the most prevalent risk factors in CAD patients with MetS.
Recent data indicate that the dyslipidemia, hyperglycemia and abdominal obesity are crucial predictors of MetS in CAD patients. Further prospective studies are recommended for more clarification.
代谢综合征（MetS）是一个全球性的健康问题，在伊朗成年人中呈上升趋势。MetS与2型糖尿病和冠状动脉疾病（CAD）的风险相关。在本研究中，我们旨在调查CAD患者中MetS及其各个组成部分的患病率。
本横断面研究对200例在心脏病科接受选择性冠状动脉造影的CAD患者进行。测量了包括腰围（WC）和体重指数在内的人体测量指标。采集血样以测定血糖和血脂谱。根据修改后的成人治疗小组第三次报告（ATP III）标准定义MetS的组成部分。
患者中MetS的患病率为49.5%（女性：55.9%；男性：40.2%；P<0.05）。患病率随年龄增长而增加。低高密度脂蛋白胆固醇（低HDL-C）（84.8%）、高空腹血糖（高FBG）（77.8%）和高WC（75.8%）是患有MetS的CAD患者中最常见的危险因素。
最新数据表明，血脂异常、高血糖和腹部肥胖是CAD患者中MetS的关键预测因素。建议进行进一步的前瞻性研究以作进一步阐明。
