Buchman Alan L, Naini Bita V, Spilker Bert
Department of Surgery, University of Illinois, Chicago, Illinois.
Department of Pathology, UCLA Medical Center, Los Angeles, California.
Semin Liver Dis. 2017 Feb;37(1):33-44. doi: 10.1055/s-0036-1597771. Epub 2017 Feb 15.
Intestinal failure-associated liver disease (IFALD), formerly known as parenteral nutrition-associated liver disease has often been listed in textbooks as an example of nonalcoholic fatty liver disease (NAFLD). However, the etiology, pathophysiology, epidemiology, histology, and progression differ substantially between the conditions defined as NAFLD and the disease, IFALD. Therefore, IFALD should not be defined or considered as a type or a cause of nonalcoholic fatty liver or nonalcoholic steatohepatitis, but rather as a distinct disease.
肠衰竭相关肝病（IFALD），以前称为肠外营养相关肝病，常被教科书列为非酒精性脂肪性肝病（NAFLD）的一个例子。然而，在定义为NAFLD的病症与IFALD疾病之间，其病因、病理生理学、流行病学、组织学及疾病进展存在很大差异。因此，IFALD不应被定义或视为非酒精性脂肪肝或非酒精性脂肪性肝炎的一种类型或病因，而应被视为一种独特的疾病。
