Rössner S, von Zweigbergk D, Ohlin A, Ryttig K
Acta Med Scand. 1987;222(1):83-8.
We report two studies, in which fibre/placebo tablets were added to a weight reduction regimen in the treatment of moderately obese women. In Study I, 60 females were treated for a two-month period with general dietary advice, providing a mean daily energy intake of 1,400 kcal. In addition, the fibre group received a 5 g dietary fibre supplement. In Study II, 45 females were treated for a three-month period with a similar programme, in which the recommended daily energy intake was 1,600 kcal and the fibre supplement 7 g/day. In both groups weight changes, hunger ratings, blood pressure, defecation pattern and possible side-effects were recorded every second week. Before treatment mean body weight was 95.4 kg (Study I) and 99.3 kg (Study II). Six patients dropped out of Study I, and four out of Study II. In Study I mean weight loss, 7.0 kg, in the fibre group was significantly higher (p less than 0.05) than 6.0 kg in the placebo group. In Study II mean weight loss in the fibre group of 6.2 kg was significantly higher than the 4.1 kg in the placebo group (p less than 0.05). No significant difference in hunger feeling between the groups was found. Systolic blood pressure was reduced in all four groups at the end of the treatment, whereas diastolic blood pressure was reduced only in the fibre group in Study II. The results suggest that dietary fibre is of additive value in the treatment of moderately obese patients. The fibre supplement, however, needs to be comparatively high.
我们报告两项研究，其中将纤维/安慰剂片剂添加到减肥方案中，用于治疗中度肥胖的女性。在研究I中，60名女性接受了为期两个月的一般饮食建议治疗，平均每日能量摄入量为1400千卡。此外，纤维组接受了5克膳食纤维补充剂。在研究II中，45名女性接受了为期三个月的类似方案治疗，其中推荐的每日能量摄入量为1600千卡，纤维补充剂为每日7克。两组均每两周记录一次体重变化、饥饿评分、血压、排便模式及可能的副作用。治疗前平均体重在研究I中为95.4千克，在研究II中为99.3千克。研究I中有6名患者退出，研究II中有4名患者退出。在研究I中，纤维组平均体重减轻7.0千克，显著高于安慰剂组的6.0千克（p小于0.05）。在研究II中，纤维组平均体重减轻6.2千克，显著高于安慰剂组的4.1千克（p小于0.05）。两组之间未发现饥饿感有显著差异。治疗结束时，所有四组的收缩压均降低，而仅研究II中的纤维组舒张压降低。结果表明，膳食纤维在治疗中度肥胖患者方面具有附加价值。然而，纤维补充剂的量需要相对较高。
