Solum T T, Ryttig K R, Solum E, Larsen S
Int J Obes. 1987;11 Suppl 1:67-71.
Sixty slightly overweight women were treated with a weight-reducing diet for 12 weeks in a randomized, double-blind, placebo-controlled study. In addition to the diet 30 women received dietary fibre tablets, whereas the remaining 30 women received identical-looking placebo tablets. During the trial both groups experienced a significant reduction in body weight (P less than 0.01). The mean weight loss 8.5 kg (7.5-9.5 kg) in the fibre group was significantly higher than that of the placebo group 6.7 kg (4.8-8.0 kg) (P less than 0.01). Both serum triglyceride and serum cholesterol concentrations were significantly lowered (P less than or equal to 0.02) after treatment in both groups. No significant differences were detected between the groups. Both systolic and diastolic blood pressure were significantly reduced (P less than 0.01) in the fibre group. No significant reduction in blood pressure was found in the placebo group. Side-effects, which were gastrointestinal in nature, were of low frequency. We conclude that supplementation with dietary fibre of the form used in this study is useful in the treatment of overweight women.
在一项随机、双盲、安慰剂对照研究中，60名轻度超重的女性接受了为期12周的减肥饮食治疗。除饮食外，30名女性服用膳食纤维片，而其余30名女性服用外观相同的安慰剂片。在试验期间，两组体重均显著下降（P<0.01）。纤维组平均体重减轻8.5kg（7.5 - 9.5kg），显著高于安慰剂组的6.7kg（4.8 - 8.0kg）（P<0.01）。两组治疗后血清甘油三酯和血清胆固醇浓度均显著降低（P≤0.02）。两组之间未检测到显著差异。纤维组收缩压和舒张压均显著降低（P<0.01）。安慰剂组血压未显著降低。副作用主要为胃肠道方面，发生率较低。我们得出结论，补充本研究中使用的膳食纤维形式对超重女性的治疗是有用的。
